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Anti-Fibrinogen-like Protein 1 [177R1] monoclonal antibody

Invented at Yale University

Info

Catalogue Number 159685
Applications ELISA
Antigen/Gene or Protein Targets Fibrinogen-like Protein 1
Synonyms FGL-1
Reactivity Mouse
Relevance Fibrinogen-like Protein 1 (FLG-1) is secreted liver protein and inhibits antigen-specific T cell activation. FLG-1 binds to lymphocyte-activation gene 3 (LAG3), independent from MHC-Class II. FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.
Host Rat
Research Area Immunology

References

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References: 1 entry

Wang et al. 2019. Cell. 176(1-2):334-347.e12. PMID: 30580966.


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References: 1 entry

Wang et al. 2019. Cell. 176(1-2):334-347.e12. PMID: 30580966.


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