Anti-protein argonaute-2 [4F9-5C5] monoclonal antibody
Invented at University Of Florida
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 158412 |
| Applications | IF IP WB |
| Antigen/Gene or Protein Targets | Protein argonaute-2 |
| Synonyms | AGO2; EIF2C2 |
| Reactivity | Human, Rat and Mouse |
| Relevance | Protein argonaute-2 plays a role in RNA interference and contains a PAZ and PIWI domain. Ago2, in humans, is responsible for the endonuclease cleavage of targeted mRNA and interacts with GW182 (mRNA binding protein) which is a marker for cytiplasmic foci called GW bodies. This monoclonal antibody may be useful in detecting functional microRNAs. |
| Host | Mouse |
| Immunogen |
Pristane-primed and recombinant full length human protein |
| Subclass | IgA kappa |
| Notes | IHC: 1:300. Also reconizes Ago1, 3 and 4. Multiple bands around 100 kDa are seen in IP/WB. |
| Research Area | Gene Expression, Epigenetics & Nuclear Signalling |
