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Anti-muscleblind-like protein 1 [3A4-1E9] monoclonal antibody

Invented at University Of Florida

Info

Catalogue Number 158409
Applications IHC IF IP WB
Antigen/Gene or Protein Targets Muscleblind-like protein 1
Synonyms Muscleblind Like Splicing Regulator 1; MBNL1
Reactivity Human, Rat and Mouse
Relevance Muscleblind-like protein 1 (MBNL1) is well characterized in its role in Myotonic dystrophy, atype of muscular dystrophy and long term genetic disorder that effects muscle function. MBLN1 regulates alternative splicing and acts as both an activator and repressor in terminal muscle differentiation. Defects in its repressor activity have been shown to lead to muscular diseases.
Host Mouse
Immunogen Recombinant MBNL1 fusion protein of human origin
Subclass IgG1 kappa
Research Area Gene Expression

References

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References: 1 entry

Mankodi et al. 2003. Ann Neurol. 54(6):760-8. PMID: 14681885.


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References: 1 entry

Mankodi et al. 2003. Ann Neurol. 54(6):760-8. PMID: 14681885.


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