Anti-muscleblind-like protein 1 [3A4-1E9] monoclonal antibody
Invented at University Of Florida
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- Inventor Info
Info
Catalogue Number | 158409 |
Applications | IHC IF IP WB |
Antigen/Gene or Protein Targets | Muscleblind-like protein 1 |
Synonyms | Muscleblind Like Splicing Regulator 1; MBNL1 |
Reactivity | Human, Rat and Mouse |
Relevance | Muscleblind-like protein 1 (MBNL1) is well characterized in its role in Myotonic dystrophy, atype of muscular dystrophy and long term genetic disorder that effects muscle function. MBLN1 regulates alternative splicing and acts as both an activator and repressor in terminal muscle differentiation. Defects in its repressor activity have been shown to lead to muscular diseases. |
Host | Mouse |
Immunogen | Recombinant MBNL1 fusion protein of human origin |
Subclass | IgG1 kappa |
Research Area | Gene Expression |