NBQ-48 small molecule (tool compound)
Invented at Ana G. Méndez University (UAGM)
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 158322 |
| Type | Inhibitor |
| Relevance | Inhibitor of growth in several cancer cell line models. This small molecule can also be used as a cell hypoxia marker in 2D and 3D colon cancer cell models. |
| On Target IC50 | 100 µM (COLO205 cells under hypoxic conditions); 128 µM +/- 3 µM (U937 cells) |
| Molecular Formula | C22H26CIN3O2 |
| lUPAC | 7-benzyl-3- nitrobenzimidazo[3,2-a]quinolinium chloride |
| Molecular Weight (g/mol) | 389.8348 |
| In vitro applications | cell hypoxia marker; fluorescence-based multiplex ELISA |
| Solubility | 3 mM in water, 10µM DMSO; 100 µg/mL in DMSO |
| Research Area | Cancer, Fluorescent Cell Imaging |
| Storage | 2-5°C in solution |
References: 3 entries
Vélez et al. 2017. Open Med Chem J. 11:54-65. PMID: 28761559.
Otero et al. 2015. J Cancer Res Ther Oncol. 1:. PMID: 26086027.
Vivas-Mejía et al. 1998. Mol Cell Biochem. 178(1-2):203-12. PMID: 9546601.
Add a reference
References: 3 entries
Vélez et al. 2017. Open Med Chem J. 11:54-65. PMID: 28761559.
Otero et al. 2015. J Cancer Res Ther Oncol. 1:. PMID: 26086027.
Vivas-Mejía et al. 1998. Mol Cell Biochem. 178(1-2):203-12. PMID: 9546601.
Add a reference
