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Info
| Catalogue Number | 158053 |
| Applications | ELISA |
| Antigen/Gene or Protein Targets | Immunoglobulin T (IgT)-heavy chain |
| Reactivity | Grass Carp |
| Relevance |
Teleost IgT is specialised in gut mucosal immunity. IgT is present in serum as monomers, whereas in the gut mucus it forms mainly noncovalent multimers similar in mass to IgM. In fish, IgT+ B cells have been identified in several species and constitute around 51% of all B cells in the intestinal mucosa. Consistent with the prevalent roles of IgT in gut immunity, most bacteria in the gut lumen are coated with IgT, and IgT responses to gut parasites are measurable only in the gut, whereas IgM responses are detected only in serum. This anti-IgT antibody may provide a useful tool to monitor vaccine performance in fish and will assist in the development of future vaccines. Anti-IgT antibody may provide a useful tool to monitor mucosal-based vaccine performance in fish and will assist in the development of future vaccines. |
| Host | Rabbit |
| Immunogen | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in carp species. |
| Formulation | Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Molecular Weight (kDa) | 65 |
| Notes |
Applications and Recommended Usage Conditions: - ELISA recommended to be used at 1/500 dilution. Use peptide immunogen as positive control. Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal. |
| Positive Control | ELISA: peptide immunogen |
| Research Area | Cell Type or Organelle Marker, Immunology |
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Inventor Information
Inventors
|
Abdo Alnabulsi |
