Anti-SAA5 [A10 P4F7*C9] monoclonal antibody
Invented by Abdo Alnabulsi
Invented at Vertebrate Antibodies Limited
- Datasheet
- References (0)
- Inventor Info
Info
| Catalogue Number | 158036 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Serum amyloid A-5 (SAA5) |
| Reactivity | Salmonids |
| Relevance |
Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA is a highly conserved, acute-phase protein (APP) synthesized predominantly by the liver. Different isoforms of SAA are expressed constitutively (constitutive SAAs, SAA4, 5) at different levels or in response to inflammatory stimuli (acute phase SAAs, SAA1-3). SAA proteins also exhibit significant immunological activity by, for example, inducing the synthesis of several cytokines and by being chemotactic for neutrophils and mast cells. SAAs are reported as a potential target in the treatment of diseases associated with inflammation. In salmon, SAA-5 has been indicated as a main acute phase response (APR) protein post 24 h in which SAA-5 is significantly induced in liver. This is a significant health marker. |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in salmonids fish species. |
| Positive Control | ELISA- peptide immunogen, recombinant protein WB- recombinant protein IHC- formalin-fixed, paraffin-embedded multi-tissues |
| Subclass | IgG1 kappa |
| Molecular Weight (kDa) | 13 |
| Strain | Balb/c |
| Notes |
Applications and Recommended Usage Conditions: - ELISA recommended to be used at 1/2, SAA5 recombinant protein - WB recommended to be used at 1/2, SAA5 recombinant protein - IHC recommended to be used at 1/2, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0. Fusion Partner is Ag 8563 Unpurified; supplied as hybridoma supernatant |
| Research Area | Cell Type or Organelle Marker, Immunology |
References
There are 0 reference entries for this reagent.
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
Inventor Information
Inventors
|
Abdo Alnabulsi |
