Anti-MMP1 [4B1] monoclonal antibody
Invented by Abdo Alnabulsi
Invented at Vertebrate Antibodies Limited
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Info
| Catalogue Number | 158035 |
| Applications | IHC |
| Antigen/Gene or Protein Targets | Activated- Matrix Metallopeptidase 1 |
| Synonyms | Interstitial Collagenase, Fibroblast Collagenase |
| Reactivity | Human |
| Relevance |
Matrix metallopeptidases (MMPs) are also named matrix metalloproteinases or matrixins. MMPs are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Matrix metalloproteinase-1 (MMP-1) also known as interstitial collagenase and fibroblast collagenase is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 breaks down the type I, II and III interstitial collagens. This antibody is significant as it recognises the activated form of MMP1. |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide |
| Positive Control | IHC- formalin-fixed, paraffin-embedded human tissues |
| Subclass | IgG1 kappa |
| Molecular Weight (kDa) | 40 |
| Strain | Balb/c |
| Notes |
Applications and Recommended Usage Conditions: - IHC recommended to be used Neat, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0. Fusion Partner is Ag 8563 Unpurified; supplied as hybridoma supernatant-FVLTEGNPRC |
| Research Area | Cell Type or Organelle Marker, Immunology |
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Inventor Information
Inventors
|
Abdo Alnabulsi |
