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Isobenzofuran analog of sclerophytin A (6h) small molecule
RECENTLY UPDATED

Invented by Dr. Matt McIntosh
Invented at University of Arkansas, Fayetteville

Info

Catalogue Number 158012
Relevance Naturally occurring products 2, 11 cyclized cembranoids have been shown to inhibit the growth of KB3 nasopharyngeal carcinoma. The standard cancer cell line used to test for chemotherapy effectiveness. The bicyclic hydroisobenzofuran is the beneficial compounds that are naturally occurring in 2, 11 cyclized cembranoids. This compound has shown inhibition of growth of KB3 cancer test cells and could be used in cancer and antibiotics research.
On Target IC50 1 μM
Research Area Cancer

References

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References: 1 entry

Bateman et al. 2009. Bioorg Med Chem Lett. 19(24):6898-901. PMID: 19896844.


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References: 1 entry

Bateman et al. 2009. Bioorg Med Chem Lett. 19(24):6898-901. PMID: 19896844.


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