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DLKP-SQ Mitox BCRP cell line

Invented at Dublin City University

Info

Catalogue Number 157983
Parental Line DLKP-SQ
Host Human
Tissue Lymph Node
Disease Keywords lung carcinoma
Relevance Sub type of lung carcinoma
Production Details DLKP-SQ resistant variant. Made resistant to mitoxanthrone, developed BCRP overexpression.
Conditional Description IC50 43ng/ml to mitoxanthrone, 1.8-fold VP-16
Research Area Cancer, Drug Discovery & Development
Growth/Phenotype Keywords monolayer
Recommended Growing Conditions DMEM/Ham's F12, 5% FCS. Split 1:5, medium change 2-3 times weekly. Freezing method: 10% DMSO in FBS
Positive Control DLKP-SQ
Notes Squamous sub-population, BCRP over-expressing model

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