DLKP-SQ Mitox BCRP cell line
Invented at Dublin City University
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Info
| Catalogue Number | 157983 |
| Parental Line | DLKP-SQ |
| Host | Human |
| Tissue | Lymph Node |
| Disease Keywords | lung carcinoma |
| Relevance | Sub type of lung carcinoma |
| Production Details | DLKP-SQ resistant variant. Made resistant to mitoxanthrone, developed BCRP overexpression. |
| Conditional Description | IC50 43ng/ml to mitoxanthrone, 1.8-fold VP-16 |
| Research Area | Cancer, Drug Discovery & Development |
| Growth/Phenotype Keywords | monolayer |
| Recommended Growing Conditions | DMEM/Ham's F12, 5% FCS. Split 1:5, medium change 2-3 times weekly. Freezing method: 10% DMSO in FBS |
| Positive Control | DLKP-SQ |
| Notes | Squamous sub-population, BCRP over-expressing model |
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