BR45 cell line
Invented at Hadassah Medical Center Hadasit Medical Research Services and Development Ltd.
Catalogue Number | 157975 |
Antigen/Gene or Protein Targets | Ovary Cancer |
Host | Human |
Tissue | Breast |
Disease Keywords | Ovary Cancer |
Model | Tumour line |
Relevance | This is an ovary cancer patient's derived cell line. Histology of serous papillary carcinoma. The line is derived from breast metastasis and it is positive for the BRCA1 c.68_69delAG, p.Glu23Valfsā17 (185delAG) mutation. When implanted to NSG mice it forms tumors. This line can serve as a platform for drug screening for cancer cells in vitro and in vivo. |
Production Details | The cells were derived from metastasis (pleural effusion) in a patient with serous papillary carcinoma. |
Research Area | Cancer, Drug Discovery & Development |
Recommended Growing Conditions | The base medium for this cell line is DMEM with 10% bovine serum. |
There are 0 reference entries for this reagent.