Cancer Research Technology
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BR58 cell line
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Antigen/Gene or Protein Targets Ovary Cancer
Host Human
Tissue Breast
Disease Keywords Ovary Cancer
Model Tumour line
Relevance This is an ovary cancer patient's derived cell line. Histology of serous papillary carcinoma. The line is derived from breast metastasis and it is positive for the BRCA1 c.68_69delAG, p.Glu23Valfsāˆ—17 (185delAG) mutation. When implanted to NSG mice it forms tumors. This line can serve as a platform for drug screening for cancer cells in vitro and in vivo.
Production Details The cells were derived from metastasis (pleural effusion) in a patient with serous papillary carcinoma.
Research Area Cancer, Drug Discovery & Development
Recommended Growing Conditions The base medium for this cell line is DMEM with 10% bovine serum.

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