BR45 cell line
Invented at Hadassah Medical Center Hadasit Medical Research Services and Development Ltd.
|Antigen/Gene or Protein Targets||Ovary Cancer|
|Disease Keywords||Ovary Cancer|
|Relevance||This is an ovary cancer patient's derived cell line. Histology of serous papillary carcinoma. The line is derived from breast metastasis and it is positive for the BRCA1 c.68_69delAG, p.Glu23Valfs∗17 (185delAG) mutation. When implanted to NSG mice it forms tumors. This line can serve as a platform for drug screening for cancer cells in vitro and in vivo.|
|Production Details||The cells were derived from metastasis (pleural effusion) in a patient with serous papillary carcinoma.|
|Research Area||Cancer, Drug Discovery & Development|
|Recommended Growing Conditions||The base medium for this cell line is DMEM with 10% bovine serum.|
There are 0 reference entries for this reagent.