Anti-Fibrinogen-like Protein 1 [177 m03] monoclonal antibody
Invented at Yale University
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- Inventor Info
Info
Catalogue Number | 157963 |
Applications | ELISA FACS IHC |
Antigen/Gene or Protein Targets | Fibrinogen-like Protein 1 |
Synonyms | FGL-1 |
Reactivity | Human |
Relevance | Fibrinogen-like Protein 1 (FLG-1) is secreted liver protein and inhibits antigen-specific T cell activation. FLG-1 binds to lymphocyte-activation gene 3 (LAG3), independent from MHC-Class II. FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells. |
Host | Mouse |
Research Area | Immunology |