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Anti-CLEC16A [4F11] monoclonal antibody
RECENTLY UPDATED

Info

Catalogue Number 157893
Applications ELISA WB
Antigen/Gene or Protein Targets C-Type Lectin Domain Containing 16A
Synonyms CLEC16A (also known as KIAA0350)
Reactivity Human
Relevance
RECENTLY UPDATED
antibody against CLEC16A (specifically binds to C-terminal human peptide CLEC16A954-980: VIVNETEADSKPSKNVARSAAVETASL)

CLEC16A is a cytosolic protein which is differentially expressed in human immune cells and is known to be highly expressed on B-lymphocytes, natural killer (NK) and dendritic cells. CLEC16A gene has been linked to several autoimmune diseases, including Addison's disease, diabetes melllitus, Crohn's disease, primary biliary cirrhosis, juvenile idiopathic arthritis, rheumatoid arthritis and multiple sclerosis. . CLEC16A has been shown to regulate various immune pathways including directly regulating leukocyte antigen class II pathway in antigen presenting cells, autophagy, mitophagy, and NK cell cytotoxicity.
Immunogen 27-mer C-terminal human peptide (CLEC16A 954-980: VIVNETEADSKPSKNVARSAAVETASL) linked to KLH
Positive Control IgG2B
Research Area Autoimmunity, Diabetes, Immunology, Neurobiology

References

There are 1 reference entries for this reagent.

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References: 1 entry

van Luijn et al. 2015. Brain. 138(Pt 6):1531-47. PMID: 25823473.


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References: 1 entry

van Luijn et al. 2015. Brain. 138(Pt 6):1531-47. PMID: 25823473.


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