Anti-RgpB (arginine-gingipain B) [18E6] monoclonal antibody
Invented at University of Georgia
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 157694 |
| Applications | IHC IP WB |
| Antigen/Gene or Protein Targets | arginine-gingipain B (RgbB) from Porphyromonas gingivalis |
| Reactivity | N/A |
| Relevance | Porphyromonas gingivalis is an oral pathogen that can induce periodontal disease. Pathogenicity is mediated in part by the secreted protein RgbP, a member of the gingipain protease family. RgbP has also been detected in the brains of Alzheimer's disease patients with levels correlating with disease markers. |
| Subclass | IgG1 |
| Notes | 18E6 recognizes a unique epitope within the immunoglobulin (Ig)–like domain of RgpB. This antibody is reactive against the protein RgpB from Porphyromonas gingivalis. |
| Research Area | Bacteriology, Drug Discovery & Development, Microbiology |
References: 2 entries
Dominy et al. 2019. Sci Adv. 5(1):eaau3333. PMID: 30746447.
Nguyen et al. 2007. J Bacteriol. 189(3):833-43. PMID: 17142394.
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References: 2 entries
Dominy et al. 2019. Sci Adv. 5(1):eaau3333. PMID: 30746447.
Nguyen et al. 2007. J Bacteriol. 189(3):833-43. PMID: 17142394.
Add a reference
