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Anti-Proinsulin [8E7.B12] monoclonal antibody

Invented at University of Georgia

Info

Catalogue Number 157687
Applications ELISA RIA
Antigen/Gene or Protein Targets Proinsulin
Reactivity Feline
Relevance A panel of monoclonal antibodies (9 total) were created to develop an assay to test for beta cell function in cats. This assay, the first of its kind, allows for the diagnosis of feline diabetes mellitus, a disease characterized by an increase in proinsulin.
Host Mouse
Immunogen recombinant proinsulin
Immunogen UniProt ID Q52PU3
Positive Control IgG2b
Notes The antibody binds to PCI and PC2 of Proinsulin
Research Area Cell Signaling & Signal Transduction

References

There are 2 reference entries for this reagent.

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References: 2 entries

Hoenig et al. 2013. J Am Vet Med Assoc. 243(9):1302-9. PMID: 24134581.

Kley et al. 2008. Domest Anim Endocrinol. 34(3):311-8. PMID: 17949938.


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References: 2 entries

Hoenig et al. 2013. J Am Vet Med Assoc. 243(9):1302-9. PMID: 24134581.

Kley et al. 2008. Domest Anim Endocrinol. 34(3):311-8. PMID: 17949938.


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Inventor Information

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