P815.Trh4 cells
Invented by Thorbald Van Hall
Invented at Leiden University and Leiden University Medical Center , Stichting Oncode Institute
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 157674 |
| Antigen/Gene or Protein Targets | Trh4 |
| Parental Line | P815 |
| Host | Mouse |
| Tissue | Bone Marrow |
| Disease Keywords | Mouse mast cell neoplasm |
| Model | Tumour line |
| Relevance | This cell line provides a model to help to understand T-cell recognition through Trh4 expression. ER-resident ceramide synthase Trh4 is a prototypic example of a neo‐antigen selectively presented by cells through various pathways. The P815 cell line has been made to over-express Trh4 and can be utilised to understand this peptide presentation process. |
| Production Details | Retroviral transduction of the mouse Trh4 gene in an IRES-GFP construct |
| Research Area | Cancer |
| Cellosaurus ID | CVCL_2154 |
References: 1 entry
References: 1 entry
Inventor Information
Inventors
|
Thorbald Van Hall |
