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P815.Trh4 cells
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Invented by Thorbald Van Hall at Leiden University Medical Center, Stichting Oncode Institute

Info

Catalogue Number 157674
Antigen/Gene or Protein Targets Trh4
Parental Line P815
Host Mouse
Tissue Bone Marrow
Disease Keywords Mouse mast cell neoplasm
Model Tumour line
Relevance This cell line provides a model to help to understand T-cell recognition through Trh4 expression. ER-resident ceramide synthase Trh4 is a prototypic example of a neo‚Äźantigen selectively presented by cells through various pathways. The P815 cell line has been made to over-express Trh4 and can be utilised to understand this peptide presentation process.
Production Details Retroviral transduction of the mouse Trh4 gene in an IRES-GFP construct
Research Area Cancer
Cellosaurus ID CVCL_2154

References

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References: 1 entry

Oliveira et al. 2011. Eur J Immunol. 41(11):3114-24. PMID: 21898382.


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References: 1 entry

Oliveira et al. 2011. Eur J Immunol. 41(11):3114-24. PMID: 21898382.


Add a reference