Anti-CD11b [OX42] monoclonal antibody
Invented at Medical Research Council , University of Oxford
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- Inventor Info
Info
Catalogue Number | 156581 |
Applications | FACS IHC IP |
Antigen/Gene or Protein Targets | CD11b |
Reactivity | Rat |
Relevance | The antibody detects rat CD11. All peritoneal macrophages and 35% of alveolar macrophages react. The antibody affects the function of complement receptor CR3. It immunoprecipitates 3 polypeptides: 160kDa, 130kDa, 95kDa. The antibody also reacts with granulocytes and dendritic cells. |
Host | Mouse |
Immunogen | Resident peritoneal cells from (PVG-RT1c x PVG RT1u)F1 and (PVG-RT1c x DA-RT1a)F1 rats |
Positive Control | IgG2a |
Myeloma Used | NS0/U |