- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 156514 |
| Backbone Size (bp) | 5428 |
| Bacterial Resistance | Ampicillin |
| Selectable Markers | Neomycin |
| Vector Type | pcDNA3.1 |
| Synonyms | nonstructural protein X, protein X, peptide X, pX |
| Antigen/Gene or Protein Targets | HBx with FLAG tag at N-terminus |
| Relevance | This vector can be used to express hepatitis B virus HBx protein in a variety of primary and cancer cells. The addition of the FLAG-epitope tag allows for detection in western and immunofluorescent cell-based studies and provides better detection ability than can currently be achieved with commercially available anti-HBx antibodies. |
| Research Area | Cancer, Virology |
| Notes | Multi-functional hepatitis B viral protein, non-structural protein X, that modulates mitochondrial function in host hepatocytes interfering with host anti-viral defenses, promoting viral transcription, and contributing to hepatocellular carcinoma development. |
References: 2 entries
Clippinger et al. 2008. J Virol. 82(14):6798-811. PMID: 18448529.
McClain et al. 2007. J Virol. 81(21):12061-5. PMID: 17699583.
Add a reference
References: 2 entries
Clippinger et al. 2008. J Virol. 82(14):6798-811. PMID: 18448529.
McClain et al. 2007. J Virol. 81(21):12061-5. PMID: 17699583.
Add a reference
Inventor Information
Inventors
|
Dr. Michael Bouchard |
