Catalogue Number
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156465 |
Applications
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IHC
WB
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Antigen/Gene or Protein Targets
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Acid-sensing ion channel (ASIC) 1a
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Reactivity
|
Mouse
|
Relevance
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Acid-sensing ion channels (ASICs) are proton-gated ion channels expressed predominantly in neurons. In the brain, the main ASIC subunits are ASIC1a, ASIC2a and ASIC2b. ASICs have been shown to regulate synaptic function, fear, learning, and are one important contributor to pain and neuronal injuries.
|
Host
|
Rabbit
|
Immunogen
|
Raised against synthetic peptide DKGVALSLDDVKRHNPC (DKG) which correlates to amino acids 479-495 of mouse ASIC1a)
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Notes
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WB; IHC (Successful only in tissue that overexpresses protein due to low endogenous levels)
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Research Area
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Neurobiology
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