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Anti-Pirt polyclonal antibody
RECENTLY UPDATED

Invented at Johns Hopkins University

Info

Catalogue Number 156435
Applications
RECENTLY UPDATED
IHC
Antigen/Gene or Protein Targets
RECENTLY UPDATED
phosphoinositide interacting regulator of TRP (Pirt)
Reactivity
RECENTLY UPDATED
Human
Relevance
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Transient receptor potential vanilloid 1 (TRPV1) is a molecular sensor of pain. Its channel activity can be modulated by several mechanisms. Phosphoinositide interacting regulator of TRP (Pirt), a membrane protein, expressed specifically in the peripheral nervous system (PNS), predominantly in nociceptive (pain) neurons has been described by several experiments indicating that Pirt is a key component of the TRPV1 complex and positively regulates TRPV1 activity. To further study this signaling pathway, a rabbit polyclonal anti-Pirt antibody that recognizes the Pirt protein has been developed.
Host
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Rabbit
Method of Purification
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affinity-purified
Research Area
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Cell Signaling & Signal Transduction, Other

References

There are 1 reference entries for this reagent.

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References: 1 entry
RECENTLY UPDATED

Kim et al. 2008. Cell. 133(3):475-85. PMID: 18455988.


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References: 1 entry
RECENTLY UPDATED

Kim et al. 2008. Cell. 133(3):475-85. PMID: 18455988.


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Inventor Information

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