Cancer Research Technology
Log in Register
Menu

R-3327 MAT-LyLu cell line

Info

Catalogue Number 156410
Antigen/Gene or Protein Targets Metastatic anaplastic tumor (MAT) cell line, highly metastatic to the lungs and the lymph nodes (MAT-LyLu).
Disease Keywords Prostate Cancer
Model Cancer Model
Relevance This cell line was derived from the "H" subline and was passaged to the AT-1 subline of the parental R3327 tumor. The "H" subline is a heterogeneous cell line as it is comprised of androgen-dependent and androgen-independent tumor cells. Passing this heterogeneous tumor cell population in intact male rats allowed for the cloning of androgen-independent cell lines which gave rise to a fast-growing metastatic, anaplastic tumor (MAT) cell line which was further characterized to be highly metastatic to the lungs and the lymph nodes (MAT-LyLu). This cell line is a valuable model for the studying prostate malignancies both in vitro and in vivo.
Research Area Cancer, Drug Discovery & Development
Cellosaurus ID CVCL_3848

References

There are 2 reference entries for this reagent.

View All References

References: 2 entries

Musialik et al. 2013. Oncol Rep. 29(5):1789-96. PMID: 23467722.

Isaacs et al. 1981. Invest Urol. 19(1):20-3. PMID: 7251319.


Add a reference

References: 2 entries

Musialik et al. 2013. Oncol Rep. 29(5):1789-96. PMID: 23467722.

Isaacs et al. 1981. Invest Urol. 19(1):20-3. PMID: 7251319.


Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor