Cancer Research Technology
Log in Register
Menu

R-3327-MAT-Lu cell line

Info

Catalogue Number 156409
Antigen/Gene or Protein Targets Metastatic anaplastic tumor that is highly metastatic in the lung
Disease Keywords Prostate Cancer
Model Cancer Model
Relevance This cell line was derived from the "H" subline and upon passage to the AT-1 subline (JHU-29) of the parental R3327 tumor. The "H" subline is a heterogeneous cell line as it is comprised of androgen-dependent and androgen-independent tumor cells. Passing this AT-1 sublinein intactmale rats allowed for the cloning of androgen-independent cell lines which gave rise to a fast-growing metastatic, anaplastic tumor (MAT) cell line which was further characterized to be highly metastatic to the lung (MAT-Lu). This cell line is a valuable model for the studying prostate malignancies both in vitro, and in vivo.DM 3852
Research Area Cancer, Drug Discovery & Development
Cellosaurus ID CVCL_3847

References

There are 2 reference entries for this reagent.

View All References

References: 2 entries

Isaacs et al. 1988. Prostate. 13(2):165-88. PMID: 3174494.

Isaacs et al. 1986. Prostate. 9(3):261-81. PMID: 3774632.


Add a reference

References: 2 entries

Isaacs et al. 1988. Prostate. 13(2):165-88. PMID: 3174494.

Isaacs et al. 1986. Prostate. 9(3):261-81. PMID: 3774632.


Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor