Anti-CUL-4A polyclonal antibody
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RECENTLY UPDATED
Invented at University of Illinois, Chicago
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 156385 |
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Applications
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ChIP ELISA IHC IP WB |
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Antigen/Gene or Protein Targets
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Cullin 4A |
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Synonyms
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CUL-4A |
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Reactivity
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Human and Mouse |
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Relevance
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CUL-4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. Moreover, CUL-4A is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a result, CUL-4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV. |
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Host
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Rabbit |
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Immunogen
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Synthetic peptide (ERDKDNPNQYHYVA) (746-759, C-terminus peptide), corresponding to human CUL-4A was conjugated to maleimide-activated keyhole limpet hemocyanin |
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Research Area
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Cancer, Cell Cycle, DNA Damage and Repair, Protein Degradation |
References: 2 entries
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RECENTLY UPDATED
Sharma et al. 2014. Open Biol. 4:130217. PMID: 24522884.
Shiyanov et al. 1999. J Biol Chem. 274(50):35309-12. PMID: 10585395.
Add a reference
References: 2 entries
RECENTLY UPDATED
RECENTLY UPDATED
Sharma et al. 2014. Open Biol. 4:130217. PMID: 24522884.
Shiyanov et al. 1999. J Biol Chem. 274(50):35309-12. PMID: 10585395.
Add a reference
