Anti-CUL-4A polyclonal antibody
Invented at University of Illinois, Chicago
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- References (2)
- Inventor Info
Info
| Catalogue Number | 156385 |
| Applications | ChIP ELISA IHC IP WB |
| Antigen/Gene or Protein Targets | Cullin 4A |
| Synonyms | CUL-4A |
| Reactivity | Human and Mouse |
| Relevance | CUL-4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. Moreover, CUL-4A is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a result, CUL-4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV. |
| Host | Rabbit |
| Immunogen | Synthetic peptide (ERDKDNPNQYHYVA) (746-759, C-terminus peptide), corresponding to human CUL-4A was conjugated to maleimide-activated keyhole limpet hemocyanin |
| Research Area | Cancer, Cell Cycle, DNA Damage and Repair, Protein Degradation |
References: 2 entries
Sharma et al. 2014. Open Biol. 4:130217. PMID: 24522884.
Shiyanov et al. 1999. J Biol Chem. 274(50):35309-12. PMID: 10585395.
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References: 2 entries
Sharma et al. 2014. Open Biol. 4:130217. PMID: 24522884.
Shiyanov et al. 1999. J Biol Chem. 274(50):35309-12. PMID: 10585395.
Add a reference
