Anti-Aβ (Abeta) [6C3] monoclonal antibody
Invented at University of Illinois, Chicago
- Datasheet
- References (5)
- Inventor Info
Info
| Catalogue Number | 156374 |
| Applications | IHC WB |
| Antigen/Gene or Protein Targets | Amyloid-β Peptide |
| Synonyms | Aβ or Abeta |
| Reactivity | Human |
| Relevance | Defects in APP are associated with the pathology of various types of Alzheimer's disease. Specially, the defective amyloid-beta-APP 40-42 peptides, which MOAB-2 targets exclusively, are major constituents of extracellular plaques and contribute cytotoxic neuronal death. |
| Host | Mouse |
| Immunogen | Human beta Amyloid. Recombinant oligomeric Aß42. Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF). |
| Positive Control | IgG2b |
| Subclass Notes | positive signal in a formalin-fixed paraffin-embedded Human Hippocampus (Alzheimer's Disease) tissue section |
| Research Area | Apoptosis and Programmed Cell Death, Fluorescent Cell Imaging, Developmental Biology, Other |
References: 5 entries
295587871
Fekete et al. 2019. Neuroscience. 405:35-46. PMID: 29522854.
Scaringi et al. 2012. Anticancer Res. 32(10):4213-23. PMID: 23060541.
Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.
Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.
Add a reference
References: 5 entries
295587871
Fekete et al. 2019. Neuroscience. 405:35-46. PMID: 29522854.
Scaringi et al. 2012. Anticancer Res. 32(10):4213-23. PMID: 23060541.
Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.
Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.
Add a reference
