Cancer Research Technology
Log in Register
Menu

Anti-Aβ (Abeta) [6C3] monoclonal antibody

Info

Catalogue Number 156374
Applications IHC WB
Antigen/Gene or Protein Targets Amyloid-β Peptide
Synonyms Aβ or Abeta
Reactivity Human
Relevance Defects in APP are associated with the pathology of various types of Alzheimer's disease. Specially, the defective amyloid-beta-APP 40-42 peptides, which MOAB-2 targets exclusively, are major constituents of extracellular plaques and contribute cytotoxic neuronal death.
Host Mouse
Immunogen Human beta Amyloid. Recombinant oligomeric Aß42. Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF).
Positive Control IgG2b
Subclass Notes positive signal in a formalin-fixed paraffin-embedded Human Hippocampus (Alzheimer's Disease) tissue section
Research Area Apoptosis and Programmed Cell Death, Fluorescent Cell Imaging, Developmental Biology, Other

References

There are 5 reference entries for this reagent.

View All References

References: 5 entries

295587871

Fekete et al. 2019. Neuroscience. 405:35-46. PMID: 29522854.

Scaringi et al. 2012. Anticancer Res. 32(10):4213-23. PMID: 23060541.

Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.

Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.


Add a reference

References: 5 entries

295587871

Fekete et al. 2019. Neuroscience. 405:35-46. PMID: 29522854.

Scaringi et al. 2012. Anticancer Res. 32(10):4213-23. PMID: 23060541.

Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.

Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.


Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor