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Anti-ICOS [4A.3A2] monoclonal antibody
RECENTLY UPDATED

Info

Catalogue Number 155247
Applications N/A
Antigen/Gene or Protein Targets
RECENTLY UPDATED
inducible T-cell co-stimulator, CD278
Reactivity N/A
Relevance
RECENTLY UPDATED
Monoclonal antibody directed against ICOS, an immune checkpoint inhibitor.

Background and Research Application
ICOS (Inducible T-cell CO Stimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is an immune checkpoint expressed on activated T cells, which has opposing functions in sustaining T cell activation and in Treg suppressive activity. ICOS plays roles in cell-cell signalling, immune responses and regulation of cell proliferation.
Immunogen UniProt ID
RECENTLY UPDATED
Q9Y6W8
Notes
RECENTLY UPDATED
Production Details
Purified using multi-step affinity chromatography with protein A.

Storage Conditions
Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles.

Concentration
1mg/ml as standard
Research Area
RECENTLY UPDATED
Immunology

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