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Anti-Thy 1 [Y19] monoclonal antibody

Invented at Yale University

Info

Catalogue Number 155243
Applications N/A
Antigen/Gene or Protein Targets Thy1, CD90
Reactivity N/A
Relevance Monoclonal antibody which can identify stem cell markers and processes within mature neurones.

Background and Research Application
Thy-1 or CD90 is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Thy-1 is expressed on thymocytes, CD34+ prothymocytes, hematopoietic stem cells, neurons, a small subset of human foetal liver cells, cord blood cells, and bone marrow cells. It is also found on a subset of immature, CD34+ cells and a distinct subset of mature CD34- cells that are CD3+CD4+. Thy-1 is involved in regulation of adhesion and signal transduction by T cells.
Immunogen UniProt ID P04216
Notes Production Details
Purified using multi-step affinity chromatography with protein A.

Storage Conditions
Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles.

Concentration
1mg/ml as standard
Research Area Immunology

References

There are 4 reference entries for this reagent.

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References: 4 entries

Knapp et al. 2010. PLoS One. 5(7):e11653. PMID: 20657836.

Roth et al. 1997. J Exp Biol. 200(Pt 14):2057-62. PMID: 9246787.

Liu et al. 1990. J Exp Med. 172(6):1735-9. PMID: 2147950.

Jones et al. 1981. Eur J Immunol. 11(7):584-92. PMID: 6974646.


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References: 4 entries

Knapp et al. 2010. PLoS One. 5(7):e11653. PMID: 20657836.

Roth et al. 1997. J Exp Biol. 200(Pt 14):2057-62. PMID: 9246787.

Liu et al. 1990. J Exp Med. 172(6):1735-9. PMID: 2147950.

Jones et al. 1981. Eur J Immunol. 11(7):584-92. PMID: 6974646.


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Inventor Information

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