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Anti-heat stable antigen [20C9] monoclonal antibody
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Info

Catalogue Number 155239
Applications N/A
Antigen/Gene or Protein Targets
RECENTLY UPDATED
Heat Stable Antigen
Reactivity N/A
Relevance
RECENTLY UPDATED
Monoclonal antibody with a broad spectrum of inhibitory effects on the expansion of T cells induced via TCR.

Background and Research Application
Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a cell adhesion molecule encoded by the CD24 gene.
Anti-HSA significantly inhibits the proliferation of CD4 T cells induced by anti-CD3 or by allogeneic LPS-activated B cells. Engagement of the TCR in the presence of this monoclonal antibody leads to functional inactivation of T cells.
Immunogen UniProt ID
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P07900
Notes
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Production Details
Purified using multi-step affinity chromatography with protein A.

Storage Conditions
Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles.

Points of Interest
Heat stable antigen has a direct costimulatory activity for clonal expansion of normal CD4 T cells.

Concentration
1mg/ml as standard
Research Area
RECENTLY UPDATED
Immunology

References

There are 3 reference entries for this reagent.

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References: 3 entries
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Li et al. 2006. J Exp Med. 203(7):1713-20. PMID: 16769998.

Bai et al. 2004. J Exp Med. 200(4):447-58. PMID: 15314074.

Liu et al. 1992. J Exp Med. 175(2):437-45. PMID: 1346270.


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References: 3 entries
RECENTLY UPDATED

Li et al. 2006. J Exp Med. 203(7):1713-20. PMID: 16769998.

Bai et al. 2004. J Exp Med. 200(4):447-58. PMID: 15314074.

Liu et al. 1992. J Exp Med. 175(2):437-45. PMID: 1346270.


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Inventor Information

No inventors are currently linked to this reagent.

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