Anti-IA of b,f,p,q,r,s,u,v [Y3JP] monoclonal antibody
Invented at Yale University
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 155236 |
| Applications | N/A |
| Antigen/Gene or Protein Targets | IA b,f,p,q,r,s,u,v |
| Reactivity | N/A |
| Relevance |
Monoclonal antibody capable of inhibiting I-A-restricted T cell responses. Background and Research Application The anti-IA monoclonal antibody reacts with mouse MHC Class II haplotypes I-Ab, I-Af, I-Ap, I-Aq, I-Ar, I-As, I-Au, I-Av, and weakly with I-Ak. This antibody is reported to inhibit I-A-restricted T cell responses. |
| Host | Mouse |
| Immunogen UniProt ID | P11911 |
| Subclass | IgG2a |
| Notes |
Production Details Purified using multi-step affinity chromatography with protein A. Storage Conditions Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles. Points of Interest This antibody reacts with I-A subregion-controlled A alpha:A beta complexes of all mouse strains apart from the responder strain (H-2d), as well as the equivalent of A alpha:A beta complexes in rats carrying seven independent haplotypes. Concentration 1mg/ml as standard |
| Research Area | Immunology |
References: 4 entries
Campisi et al. 2016. Nat Immunol. 17(9):1084-92. PMID: 27455420.
Feng et al. 2015. Nature. 528(7580):132-136. PMID: 26605529.
Guo et al. 2015. Nat Immunol. 16(10):1051-9. PMID: 26322482.
Janeway CA et al. 1984. J Immunol. 132(2):662-7. PMID: 6228596.
Add a reference
References: 4 entries
Campisi et al. 2016. Nat Immunol. 17(9):1084-92. PMID: 27455420.
Feng et al. 2015. Nature. 528(7580):132-136. PMID: 26605529.
Guo et al. 2015. Nat Immunol. 16(10):1051-9. PMID: 26322482.
Janeway CA et al. 1984. J Immunol. 132(2):662-7. PMID: 6228596.
Add a reference
