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Anti-AP-1 (Glycoprotein Ib) [MBC-1] monoclonal antibody

Info

Catalogue Number 155098
Applications ELISA
Antigen/Gene or Protein Targets Glycoprotein 1B
Synonyms GpIb
Reactivity Human
Relevance GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha.
Host Mouse
Immunogen GPIba
Positive Control IgG1
Molecular Weight (kDa) 145
Myeloma Used P3X63Ag8.653
Research Area Immunology

References

There are 3 reference entries for this reagent.

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References: 3 entries

Rosenberg et al. 2002. Blood. 100(5):1699-706. PMID: 12176890.

Sims et al. 1991. J Biol Chem. 266(12):7345-52. PMID: 1902217.

Okita et al. 1985. J Cell Biol. 100(1):317-21. PMID: 3155520.


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References: 3 entries

Rosenberg et al. 2002. Blood. 100(5):1699-706. PMID: 12176890.

Sims et al. 1991. J Biol Chem. 266(12):7345-52. PMID: 1902217.

Okita et al. 1985. J Cell Biol. 100(1):317-21. PMID: 3155520.


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