Anti-AP-1 (Glycoprotein Ib) [MBC-1] monoclonal antibody
Invented at Versiti Blood Research Institute
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 155098 |
| Applications | ELISA |
| Antigen/Gene or Protein Targets | Glycoprotein 1B |
| Synonyms | GpIb |
| Reactivity | Human |
| Relevance | GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha. |
| Host | Mouse |
| Immunogen | GPIba |
| Positive Control | IgG1 |
| Molecular Weight (kDa) | 145 |
| Myeloma Used | P3X63Ag8.653 |
| Research Area | Immunology |
References: 3 entries
Rosenberg et al. 2002. Blood. 100(5):1699-706. PMID: 12176890.
Sims et al. 1991. J Biol Chem. 266(12):7345-52. PMID: 1902217.
Okita et al. 1985. J Cell Biol. 100(1):317-21. PMID: 3155520.
Add a reference
References: 3 entries
Rosenberg et al. 2002. Blood. 100(5):1699-706. PMID: 12176890.
Sims et al. 1991. J Biol Chem. 266(12):7345-52. PMID: 1902217.
Okita et al. 1985. J Cell Biol. 100(1):317-21. PMID: 3155520.
Add a reference
