Anti-AvW-5 (von Willebrand Factor) [MBC 121.1] monoclonal antibody
Invented at Versiti Blood Research Institute
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 155097 |
| Applications | ELISA IF IP WB |
| Antigen/Gene or Protein Targets | von Willebrand Factor |
| Synonyms | vWf |
| Reactivity | Dog and Human |
| Relevance | Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding. |
| Host | Mouse |
| Immunogen | vWf - epitope lies on the C-terminal end of VWF |
| Positive Control | IgG1 |
| Molecular Weight (kDa) | 293 |
| Myeloma Used | P3X63Ag8.653 |
| Research Area | Immunology |
References: 4 entries
Jacobi et al. 2012. Blood. 119(19):4543-53. PMID: 22431572.
Haberichter et al. 2005. Blood. 105(1):145-52. PMID: 15331450.
Haberichter et al. 2000. Blood. 96(5):1808-15. PMID: 10961880.
Rosenberg et al. 1998. J Clin Invest. 101(3):613-24. PMID: 9449695.
Add a reference
References: 4 entries
Jacobi et al. 2012. Blood. 119(19):4543-53. PMID: 22431572.
Haberichter et al. 2005. Blood. 105(1):145-52. PMID: 15331450.
Haberichter et al. 2000. Blood. 96(5):1808-15. PMID: 10961880.
Rosenberg et al. 1998. J Clin Invest. 101(3):613-24. PMID: 9449695.
Add a reference
