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Anti-GpIb (CD42) [MBC 142.16] monoclonal antibody

Invented at Versiti Blood Research Institute

Info

Catalogue Number 155086
Antigen/Gene or Protein Targets Glycoprotein 1B
Synonyms GPIb
Relevance GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha.
Host Mouse
Immunogen gpIb
Positive Control IgG1
Molecular Weight (kDa) 75
Myeloma Used P3X63Ag8.653
Research Area Immunology

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