Anti-GpIb (CD42) [MBC 142.16] monoclonal antibody
Invented at Versiti Blood Research Institute
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Info
| Catalogue Number | 155086 |
| Antigen/Gene or Protein Targets | Glycoprotein 1B |
| Synonyms | GPIb |
| Relevance | GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha. |
| Host | Mouse |
| Immunogen | gpIb |
| Positive Control | IgG1 |
| Molecular Weight (kDa) | 75 |
| Myeloma Used | P3X63Ag8.653 |
| Research Area | Immunology |
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