Anti-Ag85b [4A6] monoclonal Antibody
Invented at CIC bioGUNE
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Info
| Catalogue Number | 154853 |
| Applications | ELISA |
| Antigen/Gene or Protein Targets | Ag85b |
| Synonyms | Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular alpha-antigen) |
| Reactivity | N/A |
| Relevance | Involved in cell wall mycoloylation. Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity. |
| Host | Mouse |
| Immunogen | AM(Arabionomannan)-Ag85b |
| Subclass | IgG2b |
| Molecular Weight (kDa) | 30 |
| Recommended Growing Conditions | DMEM + 10% FBS to grow and to produce antibodies DMEM+ 5% FBS |
| Notes | Reactivity-Mycobacterium tuberculosis H37Rv |
| Research Area | Immunology, Microbiology |
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