Anti-Proliferation marker [JC1] recombinant antibody
Invented at University of Oxford
- Datasheet
- References (8)
- Inventor Info
Info
Catalogue Number | 154831 |
Antigen/Gene or Protein Targets | Proliferation marker |
Reactivity | Human |
Relevance | JC1 detects a nuclear antigen, distinct from Ki67, present in proliferating cells. It is useful as a marker of proliferation in cases such as squamous cell carcinoma where the Ki67 index cannot be determined. |
Host | Mouse |
Immunogen | Pokeweed-stimulated lymphocytes |
Subclass | IgG2a |
Molecular Weight (kDa) | 212 and 123 |
Research Area | Cancer, Cell Cycle, Cell Type or Organelle Marker, Neurobiology |
References: 8 entries
Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2.
EMMPRIN, SP1 and microRNA-27a mediate physcion 8-O-β-glucopyranoside-induced apoptosis in osteosarcoma cells.
Garrido et al. 1992. J Clin Pathol. 45(10):860-5. PMID: 1430255.
Li et al. 2017. J Exp Clin Cancer Res. 36(1):58. PMID: 28427443.
Monoclonal antibody JC1: new reagent for studying cell proliferation.
Unexpected Discovery of Dichloroacetate Derived Adenosine Triphosphate Competitors Targeting Pyruvate Dehydrogenase Kinase To Inhibit Cancer Proliferation.
Wang et al. 2016. Am J Cancer Res. 6(6):1331-44. PMID: 27429847.
Zhang et al. 2016. J Med Chem. 59(7):3562-8. PMID: 27006991.
Add a reference
References: 8 entries
Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2.
EMMPRIN, SP1 and microRNA-27a mediate physcion 8-O-β-glucopyranoside-induced apoptosis in osteosarcoma cells.
Garrido et al. 1992. J Clin Pathol. 45(10):860-5. PMID: 1430255.
Li et al. 2017. J Exp Clin Cancer Res. 36(1):58. PMID: 28427443.
Monoclonal antibody JC1: new reagent for studying cell proliferation.
Unexpected Discovery of Dichloroacetate Derived Adenosine Triphosphate Competitors Targeting Pyruvate Dehydrogenase Kinase To Inhibit Cancer Proliferation.
Wang et al. 2016. Am J Cancer Res. 6(6):1331-44. PMID: 27429847.
Zhang et al. 2016. J Med Chem. 59(7):3562-8. PMID: 27006991.
Add a reference