Anti-RAD53 [F9-A1]
Invented at IFOM-IEO
- Datasheet
- References (2)
- Inventor Info
Info
| Applications | WB |
| Antigen/Gene or Protein Targets | RAD53 |
| Synonyms | CHEK2 homolog, CHK2 homolog, MEC2, RAD53 |
| Reactivity | Saccharomyces cerevisiae |
| Relevance | Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. Seems to be involved in the phosphorylation of RPH1. |
| Host | Mouse |
| Myeloma Used | Sp2/0 |
| Research Area | Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling |
References: 2 entries
Fiorani et al. 2008. Cell Cycle. 7(4):493-9. PMID: 18287812.
Characterization of the activation domain of the Rad53 checkpoint kinase.
Europe PMC ID: 18287812
Add a reference
References: 2 entries
Fiorani et al. 2008. Cell Cycle. 7(4):493-9. PMID: 18287812.
Characterization of the activation domain of the Rad53 checkpoint kinase.
Add a reference
