Cancer Research Technology
Log in Register
Menu

Anti-CD11C [118/A5] recombinant antibody
RECENTLY UPDATED

Invented at University of Oxford

Info

Catalogue Number 154809
Applications
RECENTLY UPDATED
ELISA WB
Antigen/Gene or Protein Targets
RECENTLY UPDATED
CD11C, Integrin, alpha X (complement component 3 receptor 4 subunit). ITGAX
Reactivity
RECENTLY UPDATED
Human
Relevance
RECENTLY UPDATED
The integrin alpha X chain protein (CD11c) belongs to the ß2 integrin subfamily. Integrins are cell surface receptors composed of a heterodimer containing an a and ß subunit. CD11c (the a subunit) combines with CD18 (the ß subunit) to form the leukocyte specific integrin inactivated-C3b receptor 41,2. CD11c is known to be expressed on monocytes/macrophages, granulocytes, activated B cells, in spleen and in bone marrow.
Host
RECENTLY UPDATED
Mouse
Immunogen
RECENTLY UPDATED
Synthetic peptide conjugated to KLH corresponding to the C terminus of human CD11C: ANGQIAPENGTQTPSPPSEK
Subclass
RECENTLY UPDATED
IgG2b
Positive Control
RECENTLY UPDATED
Human tonsil
Research Area
RECENTLY UPDATED
Adhesion, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

References

There are 8 reference entries for this reagent.

View All References

References: 8 entries
RECENTLY UPDATED

Ammon et al. 2000. Immunology. 100(3):364-9. PMID: 10929059.

Bilsland et al. 1994. J Immunol. 152(9):4582-9. PMID: 7512600.

Comparative analysis of integrin expression on monocyte-derived macrophages and monocyte-derived dendritic cells.

Ihanus et al. 2007. Blood. 109(2):802-10. PMID: 16985175.

Myones et al. 1988. J Clin Invest. 82(2):640-51. PMID: 2969921.

Neutrophil and monocyte cell surface p150,95 has iC3b-receptor (CR4) activity resembling CR3.

Red-cell ICAM-4 is a ligand for the monocyte/macrophage integrin CD11c/CD18: characterization of the binding sites on ICAM-4.

The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by a heterologous beta subunit and localization of a ligand recognition site to the I domain.


Add a reference

References: 8 entries
RECENTLY UPDATED

Ammon et al. 2000. Immunology. 100(3):364-9. PMID: 10929059.

Bilsland et al. 1994. J Immunol. 152(9):4582-9. PMID: 7512600.

Comparative analysis of integrin expression on monocyte-derived macrophages and monocyte-derived dendritic cells.

Ihanus et al. 2007. Blood. 109(2):802-10. PMID: 16985175.

Myones et al. 1988. J Clin Invest. 82(2):640-51. PMID: 2969921.

Neutrophil and monocyte cell surface p150,95 has iC3b-receptor (CR4) activity resembling CR3.

Red-cell ICAM-4 is a ligand for the monocyte/macrophage integrin CD11c/CD18: characterization of the binding sites on ICAM-4.

The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by a heterologous beta subunit and localization of a ligand recognition site to the I domain.


Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor