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Anti-Forssman [117C9] monoclonal Antibody
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Invented by Prof Arnoud Sonnenberg at Netherlands Cancer Institute

Info

Catalogue Number 154798
Applications IHC
Antigen/Gene or Protein Targets Forssman
Reactivity Mouse
Relevance The Forssman Antigen is a glycolipid heterophil protein and a type of heterogenetic antigen found in certain animals like dogs, horses, cats, turtles and sheep, including enteric organisms such as pneumococci. In sheep, it is found on erythrocytes but not on tissue and organs, unlike hamsters and guinea pigs whose organ cells do carry the antigen.
Host Rat
Immunogen Immunized with Mouse mammary tumors
Subclass IgM
Recommended Growing Conditions DMEM + 10% FBS ultra low IgG, 37 ⁰C 5% CO2
Notes Derived by fusing Mouse myeloma cells with spleen cells from a Rat. Clone 117C9 detects overlapping epitopes on the Forssman glycolipid hapten (GalNA1- c3aG alNAcD1 -3GalaI-4GalB1-4GlcBl-lCer). Clone 33B12 reacts with the terminal sugar sequence GalNAcd-3GalNAc and is specific for Forssman antigen.
Research Area Immunology

References

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References: 1 entry

Sonnenberg et al. 1986. J Immunol. 137(4):1264-9. PMID: 2426359.


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References: 1 entry

Sonnenberg et al. 1986. J Immunol. 137(4):1264-9. PMID: 2426359.


Add a reference