Anti-Melanoma cells [NKIM6] monoclonal Antibody
Invented at Netherlands Cancer Institute
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 154783 |
| Applications | N/A |
| Antigen/Gene or Protein Targets | Melanoma cells |
| Reactivity | Human |
| Relevance | Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. In women, they most commonly occur on the legs, while in men they are most common on the back. Sometimes they develop from a mole with changes such as an increase in size, irregular edges, change in colour, itchiness, or skin breakdown. |
| Host | Mouse |
| Immunogen | A mouse was immunized with cultured melanoma cells derived from a human melanoma metastasis. |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes |
Fusion partners: SP2/0 x spleen cells origin BALB/C. This antibody recognizes a high molecular weight proteoglycan with a molecular weight > 450 kD (chondroitin sulfate) and 250 kD (core protein). The antibody reacts strongly with melanoma cells derived from cell lines and short term cultures and reacts preferentially with melanoma cells in frozen tissue sections. The antibody can also be used to detect melanoma lesions in vivo. |
| Research Area | Cancer |
References: 2 entries
de Vries et al. 1986. Int J Cancer. 38(4):465-73. PMID: 2428758.
Buraggi et al. 1985. Cancer Res. 45(7):3378-87. PMID: 4005860.
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References: 2 entries
de Vries et al. 1986. Int J Cancer. 38(4):465-73. PMID: 2428758.
Buraggi et al. 1985. Cancer Res. 45(7):3378-87. PMID: 4005860.
Add a reference
