Anti-CD22 [3H4] monoclonal Antibody
Invented at Netherlands Cancer Institute
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Info
| Catalogue Number | 154769 |
| Applications | FACS |
| Antigen/Gene or Protein Targets | CD22 |
| Synonyms | Sialic Acid-Binding Ig-Like Lectin 2; SIGLEC2 |
| Reactivity | Human |
| Relevance | CD22 is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. |
| Host | Mouse |
| Immunogen | Daudi (human Burkitt's lymphoma cell-line) |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 135 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | IMDM + 5% FBS ultra low IgG, 37 ⁰C CO2 |
| Strain | Balb/c |
| Notes | Fusion partners: SP2/0 x spleen cells origin BALB/C. |
| Research Area | Cell Signaling & Signal Transduction, Immunology |
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