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Anti-CD56 [NKINBL1] monoclonal Antibody
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Info

Catalogue Number 154755
Applications FACS IHC WB
Antigen/Gene or Protein Targets CD56
Synonyms NCAM1; Neural Cell Adhesion Molecule 1
Reactivity Human
Relevance CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of CD56 is most stringently associated with, but certainly not limited to, natural killer cells. CD56 has been detected on other lymphoid cells, including gamma delta (γδ) Τ cells and activated CD8+ T cells, as well as on dendritic cells. CD56 has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.
Host Mouse
Immunogen CHP-212 human neurablastoma cell line.
Subclass IgG1
Molecular Weight (kDa) 140
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions IMDM + 1% ZAP, 37 ⁰C 5% CO2
Strain Balb/c
Notes Fusion partners: SP2/0 x spleen cells origin BALB/C.
Specificity: Human NCAM, neural cellular adhesion molecule.
Research Area Cell Type or Organelle Marker, Neurobiology

References

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References: 1 entry

Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.


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References: 1 entry

Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.


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