Anti-MHC class II HLA-DQ [SPVL3] monoclonal Antibody
Invented at Netherlands Cancer Institute
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 154752 |
| Applications | FACS IHC IP |
| Antigen/Gene or Protein Targets | MHC class II HLA-DQ |
| Reactivity | Human and Pig |
| Relevance | HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells. It is an αβ heterodimer of type MHC class II. The α and β chains are encoded by two loci, HLA-DQA1 and HLA-DQB1, that are adjacent to each other on chromosome band 6p21.3. Both α-chain and β-chain vary greatly. A person often produces two α-chain and two β-chain variants and thus 4 isoforms of DQ. |
| Host | Mouse |
| Immunogen | Cloned cytotoxic T lymphocytes. |
| Subclass | IgG2a |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | IMDM + 1% ZAP, 37 ⁰C 5% CO2 |
| Strain | Balb/c |
| Notes |
Fusion partners: SP2/0 x spleen cells origin BALB/C. This antibody reacts with a monomorphic determinant on HLA-DQ (MHC class II) |
| Research Area | Cell Signaling & Signal Transduction, Immunology |
References: 3 entries
te Velde et al. 1988. J Immunol. 140(5):1548-54. PMID: 3279117.
Spits et al. 1984. Eur J Immunol. 14(4):299-304. PMID: 6609821.
Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.
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References: 3 entries
te Velde et al. 1988. J Immunol. 140(5):1548-54. PMID: 3279117.
Spits et al. 1984. Eur J Immunol. 14(4):299-304. PMID: 6609821.
Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.
Add a reference
