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Catalogue Number
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154744 |
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Applications
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IHC
WB
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Antigen/Gene or Protein Targets
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Integrin α3B
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Synonyms
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ITGA3; Antigen CD61
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Reactivity
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Human
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Relevance
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ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the α3β1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin.
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Host
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Mouse
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Immunogen
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A mouse was immunized with a synthetic peptide corresponding to a 32 amino acid stretch in the cytoplasmic domain of integrin α3B including an appending N-terminal cysteine (CTRYYQIMPKYHAVRIREEERYPPPGSTLPTKK) coupled to keyhole limpet hemocyanin.
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Subclass
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IgG1
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Myeloma Used
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Sp2/0-Ag14
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Recommended Growing Conditions
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RPMI +10% FBS ultra low IgG, 37 ⁰C 5% CO2
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Strain
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Balb/c
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Notes
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Fusion partners: SP2/0 x spleen cells origin BALB/C. Recognizes specifically the cytoplasmic domain of integrin subunit α3B which is present in microvascular structures in brain and heart.
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Research Area
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Adhesion, Cell Signaling & Signal Transduction
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