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Anti-Integrin α-3A [158A3] monoclonal Antibody
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Invented by Prof Arnoud Sonnenberg at Netherlands Cancer Institute

Info

Catalogue Number 154739
Applications IHC WB
Antigen/Gene or Protein Targets Integrin α3A
Synonyms ITGA3; Antigen CD49C
Reactivity Dog and Human
Relevance ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes up half of the α3β1 integrin duplex that plays a role in neural migration and corticogenesis, acted upon by such factors as netrin-1 and reelin.
Host Mouse
Immunogen A mouse was immunized with a synthetic peptide corresponding to the cytoplasmic domain of the integrin subunit α3A including an additional N-terminal cysteine (CRTRALYEAKRQKAEMKSQPSETERLTDDY) coupled to keyhole limpet hemocyanin.
Subclass IgG2a
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions RPMI +10% FBS ultra low IgG, 37 ⁰C 5% CO2
Strain Balb/c
Notes Fusion partners: SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse. Reacts exclusively with the cytoplasmic domain of non-phosphorylated integrin subunit α3A
Research Area Adhesion, Cell Signaling & Signal Transduction

References

There are 2 reference entries for this reagent.

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References: 2 entries

de Melker et al. 1997. Lab Invest. 76(4):547-63. PMID: 9111516.

Delwel et al. 1994. Mol Biol Cell. 5(2):203-15. PMID: 8019006.


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References: 2 entries

de Melker et al. 1997. Lab Invest. 76(4):547-63. PMID: 9111516.

Delwel et al. 1994. Mol Biol Cell. 5(2):203-15. PMID: 8019006.


Add a reference