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Anti-CD56 [123C3] monoclonal Antibody
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Info

Catalogue Number 154738
Applications IHC IF IP
Antigen/Gene or Protein Targets CD56
Synonyms NCAM1; Neural Cell Adhesion Molecule 1
Reactivity Human
Relevance CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of CD56 is most stringently associated with, but certainly not limited to, natural killer cells. CD56 has been detected on other lymphoid cells, including gamma delta (γδ) Τ cells and activated CD8+ T cells, as well as on dendritic cells. CD56 has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory.
Host Mouse
Immunogen Human small cell lung cancer membrane fraction
Subclass IgG1
Molecular Weight (kDa) 140
Recommended Growing Conditions IMDM + 1% ZAP, 37 ⁰C 5% CO2
Notes Fusion partners: derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with the a membrane preparation of a small cell lung carcinoma specimen.
Research Area Cell Type or Organelle Marker, Neurobiology

References

There are 3 reference entries for this reagent.

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References: 3 entries

Kibbelaar et al. 1991. Eur J Cancer. 27(4):431-5. PMID: 1851619.

Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.

Hilkens et al. 1984. Int J Cancer. 34(2):197-206. PMID: 6206003.


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References: 3 entries

Kibbelaar et al. 1991. Eur J Cancer. 27(4):431-5. PMID: 1851619.

Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.

Hilkens et al. 1984. Int J Cancer. 34(2):197-206. PMID: 6206003.


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