Anti-CD56 [123C3] monoclonal Antibody
Invented at Netherlands Cancer Institute
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 154738 |
| Applications | IHC IF IP |
| Antigen/Gene or Protein Targets | CD56 |
| Synonyms | NCAM1; Neural Cell Adhesion Molecule 1 |
| Reactivity | Human |
| Relevance | CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of CD56 is most stringently associated with, but certainly not limited to, natural killer cells. CD56 has been detected on other lymphoid cells, including gamma delta (γδ) Τ cells and activated CD8+ T cells, as well as on dendritic cells. CD56 has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory. |
| Host | Mouse |
| Immunogen | Human small cell lung cancer membrane fraction |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 140 |
| Recommended Growing Conditions | IMDM + 1% ZAP, 37 ⁰C 5% CO2 |
| Notes | Fusion partners: derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with the a membrane preparation of a small cell lung carcinoma specimen. |
| Research Area | Cell Type or Organelle Marker, Neurobiology |
References: 3 entries
Kibbelaar et al. 1991. Eur J Cancer. 27(4):431-5. PMID: 1851619.
Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.
Hilkens et al. 1984. Int J Cancer. 34(2):197-206. PMID: 6206003.
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References: 3 entries
Kibbelaar et al. 1991. Eur J Cancer. 27(4):431-5. PMID: 1851619.
Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.
Hilkens et al. 1984. Int J Cancer. 34(2):197-206. PMID: 6206003.
Add a reference
