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Anti-CD27 [LG3A10] monoclonal Antibody
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Info

Catalogue Number 154728
Applications ELISA FACS IHC IP
Antigen/Gene or Protein Targets CD27
Synonyms Tumor Necrosis Factor Receptor Superfamily, Member 7; TNFRSF7
Reactivity Human and Mouse
Relevance CD27 is a member of the tumour necrosis factor receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK
Host Hamster
Immunogen Armenian hamster fibroblasts transfected with the mouse CD27 DNA. Screened on same transfectants.
Subclass IgG
Molecular Weight (kDa) 55
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions IMDM + 1% ZAP, 37 ⁰C 5% CO2
Strain Armenian
Notes Strain: American hamster
Research Area Cell Signaling & Signal Transduction, Immunology

References

There are 3 reference entries for this reagent.

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References: 3 entries

Hendriks et al. 2000. Nat Immunol. 1(5):433-40. PMID: 11062504.

Gravestein et al. 1996. J Exp Med. 184(2):675-85. PMID: 8760821.

Gravestein et al. 1995. Int Immunol. 7(4):551-7. PMID: 7547681.


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References: 3 entries

Hendriks et al. 2000. Nat Immunol. 1(5):433-40. PMID: 11062504.

Gravestein et al. 1996. J Exp Med. 184(2):675-85. PMID: 8760821.

Gravestein et al. 1995. Int Immunol. 7(4):551-7. PMID: 7547681.


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