Anti-CD81 [2s48] monoclonal antibody
Invented at University Of Birmingham
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 154258 |
| Applications | ELISA FACS IF WB |
| Antigen/Gene or Protein Targets | CD81 and its second extracellular domain (EC2) |
| Synonyms | 26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1, Tetraspanin-28 |
| Reactivity | Human |
| Relevance |
CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection. |
| Host | Mouse |
| Immunogen | Recombinant human CD81 |
| Immunogen UniProt ID | P60033, CD81_HUMAN |
| Myeloma Used | NS0 |
| Recommended Growing Conditions | Grown in RPMI 1640 with penicillin (100ug/ml) and 10% FBS (foetal bovine serum). |
| Strain | Balb/c |
| Research Area | Immunology, Virology |
