Anti-CD81 [1s337] monoclonal antibody
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Invented at University Of Birmingham
- Datasheet
- References (1)
- Inventor Info
Info
Catalogue Number | 154256 |
Applications
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ELISA FACS IF WB |
Antigen/Gene or Protein Targets
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CD81 and its second extracellular domain (EC2) |
Synonyms
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26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1, Tetraspanin-28 |
Reactivity
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Human |
Relevance
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CD81 is co-opted during the life cycle of diverse human pathogens: it is involved in hepatitis C virus (HCV) and Plasmodium sporozoite invasion of hepatocytes, and also contributes to the assembly and budding of human immunodeficiency virus and influenza A virus. Developed as a part of panel of murine monoclonal antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection. |
Host
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Mouse |
Immunogen
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Recombinant human CD81 |
Immunogen UniProt ID
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P60033, CD81_HUMAN |
Myeloma Used
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NS0 |
Recommended Growing Conditions
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Grown in RPMI 1640 with penicillin (100ug/ml) and 10% FBS (foetal bovine serum). |
Strain
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Balb/c |
Research Area
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Immunology, Virology |
References: 1 entry
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References: 1 entry
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