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Anti-CD81 [2s22] monoclonal antibody

Invented at University Of Birmingham

Info

Catalogue Number 154247
Applications ELISA FACS IF WB
Antigen/Gene or Protein Targets CD81 and its second extracellular domain (EC2)
Synonyms 26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1, Tetraspanin-28
Reactivity Human
Relevance CD81 is co-opted during the life cycle of diverse
human pathogens: it is involved in hepatitis C virus (HCV) and
Plasmodium sporozoite invasion of hepatocytes, and also
contributes to the assembly and budding of human immunodeficiency
virus and influenza A virus. Developed as a part of panel of murine monoclonal
antibodies against full-length CD81 to further examine and assessed their ability to inhibit or neutralize HCV infection.
Host Mouse
Immunogen Recombinant human CD81
Immunogen UniProt ID P60033, CD81_HUMAN
Myeloma Used NS0
Recommended Growing Conditions Grown in RPMI 1640 with penicillin (100ug/ml) and 10% FBS (foetal bovine serum).
Strain Balb/c
Research Area Immunology, Virology

References

There are 1 reference entries for this reagent.

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References: 1 entry

Tkachuk et al. 1975. FEBS Lett. 52(1):66-8. PMID: 1123084.


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References: 1 entry

Tkachuk et al. 1975. FEBS Lett. 52(1):66-8. PMID: 1123084.


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