Anti HA (H5N1) Hemagglutinin Protein [4F8] Monoclonal Antibody
Invented by Yee Joo Tan
Invented at A*STAR Accelerate Technologies Pte Ltd
- Datasheet
- References (4)
- Inventor Info
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| Catalogue Number | 154122 |
| Applications | IF WB |
| Antigen/Gene or Protein Targets | HA (Hemagglutinin) |
| Synonyms | Anti-HA (H5N1) [4F8] Monoclonal Antibody |
| Reactivity | N/A |
| Notes |
The sporadic outbreaks of highly pathogenic H5N1 avian influenza virus have raised public health concerns. Monoclonal antibodies (MAbs) against hemagglutinin (HA) have been increasingly used successfully for therapeutic purposes. Rabbit polyclonal antibody (PAb) anti-HA5-C was used as positive control antibody, in the form of anti-sera raised against C terminal domain of HA of H5N1 isolate (A/chicken/Hatay/ 2004(H5N1)) (Shen et al., 2008). The protein fragment used to generate this antibody contains the residues from 330-505 (H3 numbering) in the ectodomain of HA. |
| Research Area | Microbiology, Other |
References: 4 entries
Paul et al. 2017. Antiviral Res. 144:299-310. PMID: 28633988.
A cross-clade H5N1 influenza A virus neutralizing monoclonal antibody binds to a novel epitope within the vestigial esterase domain of hemagglutinin.
Europe PMC ID: 28633988
Shen et al. 2008. J Med Virol. 80(11):1972-83. PMID: 18814259.
Comparing the antibody responses against recombinant hemagglutinin proteins of avian influenza A (H5N1) virus expressed in insect cells and bacteria.
Europe PMC ID: 18814259
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References: 4 entries
Paul et al. 2017. Antiviral Res. 144:299-310. PMID: 28633988.
A cross-clade H5N1 influenza A virus neutralizing monoclonal antibody binds to a novel epitope within the vestigial esterase domain of hemagglutinin.
Shen et al. 2008. J Med Virol. 80(11):1972-83. PMID: 18814259.
Comparing the antibody responses against recombinant hemagglutinin proteins of avian influenza A (H5N1) virus expressed in insect cells and bacteria.
Add a reference
Inventor Information
Inventors
|
Yee Joo Tan |
