Anti-Mycobacterial 30-kDa [5F9]
Invented by Professor Pranab K Das
Invented at
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 154076 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Mycobacterial 30-kDa |
| Reactivity | Mycobacterium bovis |
| Relevance | Proteins of the antigen 85 complex in the 30-kDa region secreted by live mycobacteria are important in the immune response against mycobacterial infections and play an important biological role in the host-parasite interaction. This antibody recognises antigens 85A (MPT44), 85B (MPT59) and 85C (MPT45) |
| Host | Mouse |
| Immunogen | 30-kDa antigen isolated from M.tuberculosis (RIVM-strain 7114) |
| Positive Control | M.tuberculosis |
| Subclass | IgG1 |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | RPMI 1640 |
| Strain | Balb/c |
| Notes | Reacts with M.bovisBCG, M.tuberculosis complex and M.leprae. Does not react with E.coli. The 5F9 epitope is found specifically in the cytosol fraction from M.tuberculosis culture filtrates. |
| Research Area | Bacteriology, Immunology, Microbiology |
References: 4 entries
Rambukkana et al. 1992. Infect Immun. 60(12):5172-81. PMID: 1280626.
Heterogeneity of monoclonal antibody-reactive epitopes on mycobacterial 30-kilodalton-region proteins and the secreted antigen 85 complex and demonstration of antigen 85B on the Mycobacterium leprae cell wall surface.
Europe PMC ID: 1280626
Rambukkana et al. 1991. Scand J Immunol. 33(6):763-75. PMID: 1904624.
Subcellular distribution of monoclonal antibody defined epitopes on immunodominant Mycobacterium tuberculosis proteins in the 30-kDa region: identification and localization of 29/33-kDa doublet proteins on mycobacterial cell wall.
Europe PMC ID: 1904624
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References: 4 entries
Rambukkana et al. 1992. Infect Immun. 60(12):5172-81. PMID: 1280626.
Heterogeneity of monoclonal antibody-reactive epitopes on mycobacterial 30-kilodalton-region proteins and the secreted antigen 85 complex and demonstration of antigen 85B on the Mycobacterium leprae cell wall surface.
Rambukkana et al. 1991. Scand J Immunol. 33(6):763-75. PMID: 1904624.
Subcellular distribution of monoclonal antibody defined epitopes on immunodominant Mycobacterium tuberculosis proteins in the 30-kDa region: identification and localization of 29/33-kDa doublet proteins on mycobacterial cell wall.
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